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Oxford University Press is a department of the University of Oxford. Critical Care Trauma Centre. The following pages are intended for viewing by healthcare professionals residing in France only.
The following pages are intended for viewing by healthcare professionals residing in the UK only. The CPB circuit utilized non-heparin bonded non-coated tubing, and a cell saver reservoir was spliced into the CPB circuit as a cardiotomy reservoir.
Argatroban | Intravenous Infusion | Direct Thrombin Inhibitors
By clicking to enter this site, you are confirming that you are a Infoormation Professional in one of these countries. Rewarming was commenced and the proximal anastomosis was performed. The patient was successfully weaned off cardiopulmonary bypass, with the Argatroban being stopped once cardiac activity had recommenced and the aortic cross-clamp had been removed. Clean Hands Save Lives. Argatroban is given as a continuous intravenous infusion.
Media News Contact Us. During that admission the patient developed argaroban marked rash and itching after administration of intravenous heparin, which was documented by the medical staff.
The procedure was performed with a radial arterial line; non-heparin coated right internal jugular central venous and Swan—Ganz catheter, and transesophageal echocardiogram. The patient was decannulated and all surgical sources of bleeding stopped. Inhibition of factor IXa by the pegnivacogin system during cardiopulmonary bypass: Sign In or Create an Account.
Can thromboelastography predict which patients with heparin-induced thrombocytopenia may suffer thrombotic complications of type II?
Initial dose by continuous infusion: Consideration is also being given to utilizing Argatroban in the CPB circuit in case we need to return to cardiopulmonary bypass. Test Developed in Japan, argatroban was the first licensed synthetic direct thrombin inhibitor. Email alerts New issue alert.
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Citing articles via Web of Informafion Preoperative consultation by the allergologist was obtained and the patient underwent allergy testing for porcine heparin, which was negative. Successful use of argatroban as a heparin substitute during cardiopulmonary bypass: The following pages are intended for viewing by healthcare professionals residing in Germany only.
Denmark Norway Sweden Italy Finland. Use of Argatroban for anticoagulation during cardiopulmonary bypass in a patient with heparin allergy Alan I. Around Europe You can find specific information on our products in individual countries by choosing the relevant country infomration the menu below: The use of argatroban as an anticoagulant for cardiopulmonary bypass in cardiac operations.
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Seuraavat sivut on tarkoitettu katseltavaksi terveydenhuollon ammattilaiset asuvat Suomessa vain. In the future we will consider continuing the Argatroban infusion until all the blood in the reservoir is retransfused, rather than stopping it immediately following removal of the cross-clamp as we aragtroban in this case.
Where can I go for care during the holidays? Bleeding post CPB was corrected with administration of appropriate blood products.
ARGATROBAN | LHSC
Postoperatively the patient did well. The following pages are intended for viewing by healthcare professionals residing in Norway only. Door op “doorgaan” hieronder te klikken, verklaart u dat u een ingezetene bent van Nederland en dat u de gebruiksvoorwaarden ragatroban deze website aanvaardt. We report the case of a patient with a heparin allergy requiring cardiopulmonary bypass CPB for mitral valve replacement. You can find specific information on our products in individual countries by choosing the relevant country from the menu below:.
However, this may delay the achievement of adequate hemostasis prior to closing. This patient had a documented history of an allergic reaction to heparin, and we chose to use Argatroban for CPB to avoid a potential allergic reaction, although the allergy testing for porcine heparin was negative.